The Sacrifice of Jesus Christ

It is heredity, much the same way your height, eye color, skin color, or hair color have been written into your DNA by the combination of your parents DNA, the taint of sin has been written on your soul by the first betrayal of God by your ultimate parents.  Adam and Eve walked with God in the garden - in the perfect paradise God created - and there was only one rule. 

And the Lord God commanded the man, saying "Of every tree of the garden you may freely eat; but of the tree of the knowledge of good and evil you shall not eat, for in the day that you eat of it you shall surely die. 
Genesis 2:16-17

It is the willful breaking of this first rule - the Original sin as it has been called - that separated humankind from God.  For, while it is possible to have an interesting discussion around the idea that God laid this rule down before Eve was created and thus she wasn't truly to blame or that Adam was tricked by his perfectly attractive and naked wife and thus cannot be held responsible, the Original Sin not only includes the breaking of the rule, but the fact that both Adam and then Eve lied to God by blaming another for their actions.  One can only wonder what would have happened had they confessed freely their guilt, but they did not and thus all of their descendants are tainted by this sin.

Isaiah sums up the problem plainly: 

Your wrongheaded lives caused the split between you and God.  Your sins got between you so that He doesn't hear.
Isaiah 59:2 (The Message)

It’s your sins that have cut you off from God.  Because of your sins, He has turned away and will not listen anymore.
Isaiah 59:2 (New Living Translation)

We are made right with God by placing our faith in Jesus Christ. And this is true for everyone who believes, no matter who we are.  For everyone has sinned; we all fall short of God’s glorious standard.  Yet God, with undeserved kindness, declares that we are righteous. He did this through Christ Jesus when He freed us from the penalty for our sins.  For God presented Jesus as the sacrifice for sin. People are made right with God when they believe that Jesus sacrificed his life, shedding His blood. This sacrifice shows that God was being fair when He held back and did not punish those who sinned in times past, for He was looking ahead and including them in what He would do in this present time. God did this to demonstrate His righteousness, for He Himself is fair and just, and He declares sinners to be right in His sight when they believe in Jesus.
Romans 3:22-26
(New Living Translation)